Contura, fostering innovation in the medical industry
Founded in 2000, Contura developed its patented hydrogel, comprising 2.5% polyacrylamide mixed with 97.5% purified water, to provide soft tissue support wherever in the body it is needed. In 2003, Contura launched Bulkamid for the treatment of stress urinary incontinence in women, becoming a leading treatment for this widespread condition and now sold across Europe and beyond. Following FDA approval in 2020, it was launched in the US, prompting widespread medical interest and attracting the attention of various markets. Its uptake was impressive.
After seeking the expertise of BNP Paribas, in 2021 Contura’s Women’s Health business, including Bulkamid, was divested to Axonics, a Nasdaq-listed medical company based in California with a current market capitalisation of $3.4 billion. This allowed Contura to concentrate further on its strategy to continue developing and manufacturing injectable hydrogels for use across other areas – mainly orthopaedics and animal health.
“As we navigate this strategy, it's important that we have a good financial partner in BNP Paribas that can help us and challenge us on our thinking so that we can be more sure of achieving our bold ambitions,” says Rakesh Tailor, the CEO of Contura. “Our ambition for Contura’s hydrogel is to be the leading treatment for osteoarthritis in animals and in humans.”
A deal benefiting both parties
BNP Paribas acted as exclusive financial advisor to Contura during the $235 million transaction in February 2021, which allowed Contura to invest in developing, manufacturing and commercialising other products with its hydrogel. It also provided the funds to build, own and operate a newly expanded manufacturing facility in Denmark, which continues to supply Bulkamid to Axonics.
"Contura, like many of our healthcare clients, is innovative with strong growth potential. BNP Paribas is well equipped to assist strategically and from a capital structure perspective,” says Dr Zahid Moneer, Managing Director for Healthcare at BNP Paribas.
Since 2021, Contura has launched Arthrosamid in Europe, which provides patients with relief from the symptoms of osteoarthritis. In animal health, Contura has launched ArthramidVet in the US for lameness in horses, which will be extended to small animals too.
Rakesh Tailor explains the potential: “There are a number of products in the market that offer some sort of ‘bioscaffold’ capability, but they're all temporary based. Contura’s mission was to develop something with the same physical properties as soft tissue that can provide long lasting structural support. No one in the world today has been able to make a gel that can be put with soft tissue that will stand the test of time. With our hydrogel, we see the clinical benefits to patients lasting years, not months.”
Into the future with orthopaedics and animal health
For both human orthopaedics and animal health, Contura has ambitious plans for expansion in the US, Europe and beyond. It aims for its hydrogel to become a leading treatment in osteoarthritis over the next five years in both animals and humans. For that reason, the manufacturing facility in Denmark is being expanded to cater for the increased demand. Furthermore, there is a wealth of other potential treatments – ultimately for anywhere in the body where reinforced support and structure are needed.
However, there are many challenges when it comes to running a medical technology company, according to Rakesh Tailor. They include regulations, supply chains, capital equipment, funding and market access – especially in Europe – and actually ensuring that production reaches demand. On top of that, Contura aims to expand the capacity of its manufacturing facility from 300,000 syringes a year in 2023, to reach 1.3 million in 2026 and, depending on uptake, as many as 5 million by 2030. “Ultimately, we're trying to expand our markets and make our hydrogel available to patients who need it wherever they are in the world. So we are happy to have BNP Paribas alongside us as we develop our ambitious plans,” says Rakesh Tailor.